O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 F 0 19 19 1.000 0.894 View mutations
202 L 7 12 19 0.574 0.617 View mutations
203 K 14 5 19 0.267 0.376 View mutations
204 S 6 13 19 0.677 0.624 View mutations
205 D 4 15 19 0.775 0.657 View mutations
206 I 3 16 19 0.854 0.609 View mutations
207 Y 0 19 19 0.998 0.802 View mutations
208 L 1 18 19 0.926 0.813 View mutations
209 E 1 18 19 0.931 0.670 View mutations
210 Y 11 8 19 0.361 0.472 View mutations
211 T 6 13 19 0.612 0.574 View mutations
212 R 1 18 19 0.949 0.565 View mutations
213 T 1 18 19 0.961 0.548 View mutations
214 G 0 19 19 0.992 0.654 View mutations
215 S 12 7 19 0.434 0.478 View mutations
216 E 0 19 19 0.997 0.630 View mutations
217 S 2 17 19 0.832 0.531 View mutations
218 P 0 19 19 0.979 0.559 View mutations
219 K 3 16 19 0.818 0.450 View mutations
220 V 19 0 19 0.006 0.442 View mutations
221 C 19 0 19 0.013 0.505 View mutations
222 S 19 0 19 0.001 0.497 View mutations
223 D 19 0 19 0.000 0.366 View mutations
224 Q 19 0 19 0.019 0.539 View mutations
225 S 18 1 19 0.058 0.556 View mutations