O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 Q 19 0 19 0.004 0.789 View mutations
252 D 19 0 19 0.003 0.795 View mutations
253 M 17 2 19 0.133 0.759 View mutations
254 D 19 0 19 0.001 0.802 View mutations
255 E 19 0 19 0.026 0.804 View mutations
256 D 19 0 19 0.018 0.831 View mutations
257 D 19 0 19 0.014 0.898 View mutations
258 G 19 0 19 0.006 0.804 View mutations
259 R 19 0 19 0.013 0.836 View mutations
260 D 19 0 19 0.042 0.737 View mutations
261 A 16 3 19 0.204 0.717 View mutations
262 A 14 5 19 0.291 0.626 View mutations
263 P 19 0 19 0.040 0.699 View mutations
264 P 19 0 19 0.034 0.711 View mutations
265 G 19 0 19 0.018 0.720 View mutations
266 R 19 0 19 0.000 0.621 View mutations
267 L 5 14 19 0.781 0.410 View mutations
268 P 12 7 19 0.341 0.524 View mutations
269 Q 16 3 19 0.204 0.598 View mutations
270 K 16 3 19 0.152 0.586 View mutations
271 L 10 9 19 0.489 0.450 View mutations
272 L 19 0 19 0.014 0.579 View mutations
273 L 19 0 19 0.007 0.646 View mutations
274 E 12 7 19 0.367 0.495 View mutations
275 T 19 0 19 0.016 0.692 View mutations