O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 A 8 11 19 0.642 0.429 View mutations
277 A 19 0 19 0.023 0.784 View mutations
278 P 19 0 19 0.001 0.763 View mutations
279 R 15 4 19 0.257 0.628 View mutations
280 V 19 0 19 0.032 0.741 View mutations
281 S 15 4 19 0.179 0.682 View mutations
282 S 19 0 19 0.009 0.791 View mutations
283 S 17 2 19 0.085 0.694 View mutations
284 R 16 3 19 0.223 0.641 View mutations
285 R 15 4 19 0.227 0.595 View mutations
286 Y 19 0 19 0.008 0.725 View mutations
287 S 19 0 19 0.002 0.720 View mutations
288 E 7 12 19 0.545 0.413 View mutations
289 G 19 0 19 0.021 0.703 View mutations
290 R 17 2 19 0.133 0.703 View mutations
291 E 2 17 19 0.822 0.319 View mutations
292 F 9 10 19 0.522 0.453 View mutations
293 R 19 0 19 0.000 0.698 View mutations
294 Y 18 1 19 0.055 0.804 View mutations
295 G 17 2 19 0.074 0.728 View mutations
296 S 19 0 19 0.000 0.743 View mutations
297 W 12 7 19 0.421 0.530 View mutations
298 R 9 10 19 0.510 0.448 View mutations
299 E 1 18 19 0.950 0.353 View mutations
300 P 6 13 19 0.719 0.409 View mutations