O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 L 16 3 19 0.218 0.484 View mutations
177 I 4 15 19 0.728 0.546 View mutations
178 D 7 12 19 0.543 0.553 View mutations
179 P 9 10 19 0.564 0.509 View mutations
180 A 4 15 19 0.772 0.615 View mutations
181 M 18 1 19 0.072 0.313 View mutations
182 F 6 13 19 0.740 0.620 View mutations
183 D 1 18 19 0.941 0.710 View mutations
184 Q 0 19 19 0.999 0.692 View mutations
185 A 3 16 19 0.881 0.709 View mutations
186 Q 8 11 19 0.589 0.550 View mutations
187 T 7 12 19 0.651 0.560 View mutations
188 E 0 19 19 0.982 0.734 View mutations
189 I 1 18 19 0.944 0.728 View mutations
190 Q 16 3 19 0.193 0.351 View mutations
191 A 5 14 19 0.654 0.516 View mutations
192 T 7 12 19 0.583 0.507 View mutations
193 M 3 16 19 0.789 0.662 View mutations
194 E 0 19 19 1.000 0.808 View mutations
195 E 8 11 19 0.542 0.524 View mutations
196 N 17 2 19 0.184 0.385 View mutations
197 T 4 15 19 0.761 0.622 View mutations
198 Y 0 19 19 0.980 0.879 View mutations
199 P 0 19 19 0.986 0.911 View mutations
200 S 4 15 19 0.775 0.601 View mutations