O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 V 18 1 19 0.072 0.559 View mutations
302 N 19 0 19 0.008 0.579 View mutations
303 P 10 9 19 0.515 0.440 View mutations
304 Y 2 17 19 0.880 0.357 View mutations
305 Y 19 0 19 0.026 0.601 View mutations
306 V 10 9 19 0.379 0.441 View mutations
307 N 17 2 19 0.113 0.553 View mutations
308 A 18 1 19 0.091 0.575 View mutations
309 G 17 2 19 0.124 0.490 View mutations
310 Y 16 3 19 0.163 0.541 View mutations
311 A 19 0 19 0.050 0.546 View mutations
312 L 19 0 19 0.010 0.587 View mutations
313 A 19 0 19 0.001 0.388 View mutations
314 P 3 16 19 0.730 0.472 View mutations
315 A 7 12 19 0.621 0.437 View mutations
316 T 15 4 19 0.289 0.430 View mutations
317 S 9 10 19 0.539 0.431 View mutations
318 A 17 2 19 0.137 0.487 View mutations
319 N 14 5 19 0.275 0.480 View mutations
320 D 13 6 19 0.392 0.468 View mutations
321 S 0 19 19 0.998 0.571 View mutations
322 E 1 18 19 0.968 0.629 View mutations
323 Q 10 9 19 0.451 0.498 View mutations
324 Q 1 18 19 0.967 0.535 View mutations
325 S 0 19 19 1.000 0.572 View mutations