O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 L 3 16 19 0.846 0.570 View mutations
327 S 1 18 19 0.963 0.513 View mutations
328 S 0 19 19 1.000 0.521 View mutations
329 D 0 19 19 0.985 0.558 View mutations
330 A 4 15 19 0.768 0.461 View mutations
331 D 1 18 19 0.963 0.508 View mutations
332 T 1 18 19 0.942 0.445 View mutations
333 L 3 16 19 0.797 0.473 View mutations
334 S 0 19 19 1.000 0.504 View mutations
335 L 2 17 19 0.865 0.598 View mutations
336 T 9 10 19 0.543 0.431 View mutations
337 D 3 16 19 0.789 0.587 View mutations
338 S 14 5 19 0.285 0.493 View mutations
339 S 16 3 19 0.138 0.464 View mutations
340 V 3 16 19 0.824 0.536 View mutations
341 D 16 3 19 0.179 0.456 View mutations
342 G 14 5 19 0.272 0.486 View mutations
343 I 5 14 19 0.734 0.504 View mutations
344 P 0 19 19 1.000 0.498 View mutations
345 P 14 5 19 0.230 0.466 View mutations
346 Y 6 13 19 0.650 0.443 View mutations
347 R 0 19 19 0.991 0.467 View mutations
348 I 16 3 19 0.182 0.505 View mutations
349 R 7 12 19 0.629 0.436 View mutations
350 K 16 3 19 0.192 0.414 View mutations