O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 Q 18 1 19 0.061 0.427 View mutations
352 H 18 1 19 0.075 0.451 View mutations
353 R 5 14 19 0.752 0.460 View mutations
354 R 1 18 19 0.946 0.486 View mutations
355 E 3 16 19 0.840 0.547 View mutations
356 M 14 5 19 0.261 0.475 View mutations
357 Q 13 6 19 0.353 0.498 View mutations
358 E 0 19 19 0.994 0.555 View mutations
359 S 0 19 19 0.999 0.505 View mutations
360 V 9 10 19 0.525 0.502 View mutations
361 Q 10 9 19 0.436 0.429 View mutations
362 V 1 18 19 0.947 0.568 View mutations
363 N 0 19 19 1.000 0.581 View mutations
364 G 0 19 19 1.000 0.627 View mutations
365 R 6 13 19 0.671 0.452 View mutations
366 V 2 17 19 0.905 0.579 View mutations
367 P 0 19 19 0.998 0.573 View mutations
368 L 0 19 19 0.991 0.620 View mutations
369 P 3 16 19 0.831 0.556 View mutations
370 H 13 6 19 0.377 0.497 View mutations
371 I 5 14 19 0.699 0.456 View mutations
372 P 10 9 19 0.460 0.495 View mutations
373 R 0 19 19 0.981 0.528 View mutations
374 T 6 13 19 0.726 0.442 View mutations
375 Y 10 9 19 0.509 0.437 View mutations