O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
376 R 18 1 19 0.142 0.410 View mutations
377 V 11 8 19 0.453 0.423 View mutations
378 P 0 19 19 1.000 0.601 View mutations
379 K 1 18 19 0.923 0.551 View mutations
380 E 0 19 19 0.995 0.574 View mutations
381 V 3 16 19 0.853 0.513 View mutations
382 R 1 18 19 0.935 0.542 View mutations
383 V 4 15 19 0.793 0.522 View mutations
384 E 7 12 19 0.634 0.438 View mutations
385 P 0 19 19 0.992 0.585 View mutations
386 Q 14 5 19 0.352 0.428 View mutations
387 K 1 18 19 0.873 0.447 View mutations
388 F 3 16 19 0.805 0.548 View mutations
389 A 7 12 19 0.674 0.525 View mutations
390 E 18 1 19 0.073 0.404 View mutations
391 E 16 3 19 0.237 0.389 View mutations
392 L 3 16 19 0.807 0.544 View mutations
393 I 6 13 19 0.637 0.533 View mutations
394 H 18 1 19 0.104 0.440 View mutations
395 R 18 1 19 0.077 0.467 View mutations
396 L 10 9 19 0.501 0.495 View mutations
397 E 2 17 19 0.877 0.538 View mutations
398 A 13 6 19 0.266 0.427 View mutations
399 V 18 1 19 0.031 0.396 View mutations
400 Q 10 9 19 0.516 0.496 View mutations