O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 R 1 18 19 0.936 0.467 View mutations
402 T 15 4 19 0.242 0.411 View mutations
403 R 7 12 19 0.644 0.516 View mutations
404 E 0 19 19 0.998 0.514 View mutations
405 A 18 1 19 0.075 0.408 View mutations
406 E 12 7 19 0.342 0.439 View mutations
407 E 12 7 19 0.379 0.418 View mutations
408 K 2 17 19 0.905 0.433 View mutations
409 L 6 13 19 0.676 0.535 View mutations
410 E 10 9 19 0.492 0.495 View mutations
411 E 0 19 19 0.980 0.619 View mutations
412 R 0 19 19 1.000 0.651 View mutations
413 L 0 19 19 1.000 0.590 View mutations
414 K 1 18 19 0.945 0.527 View mutations
415 R 8 11 19 0.531 0.507 View mutations
416 V 0 19 19 1.000 0.701 View mutations
417 R 0 19 19 0.975 0.568 View mutations
418 M 9 10 19 0.535 0.501 View mutations
419 E 2 17 19 0.886 0.511 View mutations
420 E 0 19 19 0.996 0.478 View mutations
421 E 18 1 19 0.056 0.493 View mutations
422 G 19 0 19 0.018 0.508 View mutations
423 E 5 14 19 0.756 0.377 View mutations
424 D 8 11 19 0.595 0.431 View mutations
425 G 19 0 19 0.000 0.728 View mutations