O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
426 D 17 2 19 0.117 0.710 View mutations
427 P 15 4 19 0.192 0.660 View mutations
428 S 12 7 19 0.395 0.583 View mutations
429 S 19 0 19 0.029 0.853 View mutations
430 G 18 1 19 0.037 0.759 View mutations
431 P 19 0 19 0.026 0.860 View mutations
432 P 19 0 19 0.001 0.904 View mutations
433 G 19 0 19 0.000 0.807 View mutations
434 P 19 0 19 0.015 0.829 View mutations
435 C 19 0 19 0.014 0.781 View mutations
436 H 19 0 19 0.002 0.770 View mutations
437 K 19 0 19 0.006 0.710 View mutations
438 L 9 10 19 0.541 0.453 View mutations
439 P 13 6 19 0.301 0.601 View mutations
440 P 16 3 19 0.208 0.736 View mutations
441 A 14 5 19 0.275 0.644 View mutations
442 P 19 0 19 0.000 0.862 View mutations
443 A 19 0 19 0.000 0.823 View mutations
444 W 18 1 19 0.140 0.808 View mutations
445 H 19 0 19 0.003 0.790 View mutations
446 H 19 0 19 0.000 0.783 View mutations
447 F 19 0 19 0.000 0.705 View mutations
448 P 19 0 19 0.004 0.744 View mutations
449 P 18 1 19 0.060 0.695 View mutations
450 R 18 1 19 0.118 0.657 View mutations