O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
451 C 19 0 19 0.000 0.709 View mutations
452 V 17 2 19 0.094 0.685 View mutations
453 D 19 0 19 0.057 0.679 View mutations
454 M 19 0 19 0.005 0.801 View mutations
455 G 18 1 19 0.035 0.741 View mutations
456 C 18 1 19 0.072 0.765 View mutations
457 A 19 0 19 0.007 0.813 View mutations
458 G 12 7 19 0.358 0.537 View mutations
459 L 18 1 19 0.037 0.661 View mutations
460 R 19 0 19 0.000 0.653 View mutations
461 D 19 0 19 0.051 0.485 View mutations
462 A 12 7 19 0.363 0.465 View mutations
463 H 12 7 19 0.448 0.447 View mutations
464 E 13 6 19 0.313 0.400 View mutations
465 E 0 19 19 0.998 0.524 View mutations
466 N 1 18 19 0.932 0.529 View mutations
467 P 0 19 19 1.000 0.635 View mutations
468 E 6 13 19 0.687 0.544 View mutations
469 S 1 18 19 0.902 0.549 View mutations
470 I 0 19 19 0.986 0.649 View mutations
471 L 0 19 19 1.000 0.654 View mutations
472 D 12 7 19 0.375 0.454 View mutations
473 E 18 1 19 0.066 0.363 View mutations
474 H 2 17 19 0.885 0.674 View mutations
475 V 5 14 19 0.738 0.603 View mutations