O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
476 Q 16 3 19 0.139 0.455 View mutations
477 R 8 11 19 0.544 0.526 View mutations
478 V 8 11 19 0.600 0.535 View mutations
479 L 1 18 19 0.949 0.671 View mutations
480 R 1 18 19 0.946 0.547 View mutations
481 T 0 19 19 1.000 0.558 View mutations
482 P 1 18 19 0.956 0.571 View mutations
483 G 4 15 19 0.784 0.503 View mutations
484 R 9 10 19 0.489 0.443 View mutations
485 Q 16 3 19 0.216 0.533 View mutations
486 S 0 19 19 1.000 0.368 View mutations
487 P 0 19 19 0.999 0.317 View mutations
488 G 16 3 19 0.230 0.587 View mutations
489 P 17 2 19 0.091 0.703 View mutations
490 G 19 0 19 0.000 0.752 View mutations
491 H 16 3 19 0.129 0.680 View mutations
492 R 6 13 19 0.705 0.358 View mutations
493 S 16 3 19 0.226 0.655 View mutations
494 P 17 2 19 0.143 0.692 View mutations
495 D 12 7 19 0.323 0.552 View mutations
496 S 18 1 19 0.090 0.782 View mutations
497 G 15 4 19 0.354 0.681 View mutations
498 H 8 11 19 0.558 0.425 View mutations
499 V 16 3 19 0.132 0.717 View mutations
500 A 19 0 19 0.042 0.847 View mutations