O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
501 K 17 2 19 0.131 0.763 View mutations
502 M 12 7 19 0.376 0.595 View mutations
503 P 14 5 19 0.324 0.706 View mutations
504 V 17 2 19 0.129 0.852 View mutations
505 A 15 4 19 0.260 0.732 View mutations
506 L 15 4 19 0.184 0.731 View mutations
507 G 19 0 19 0.001 0.885 View mutations
508 G 19 0 19 0.014 0.979 View mutations
509 A 19 0 19 0.002 0.932 View mutations
510 A 16 3 19 0.184 0.788 View mutations
511 S 18 1 19 0.064 0.885 View mutations
512 G 15 4 19 0.191 0.677 View mutations
513 H 18 1 19 0.098 0.823 View mutations
514 G 9 10 19 0.583 0.460 View mutations
515 K 5 14 19 0.737 0.317 View mutations
516 H 18 1 19 0.064 0.860 View mutations
517 V 19 0 19 0.000 0.888 View mutations
518 P 18 1 19 0.152 0.842 View mutations
519 K 4 15 19 0.797 0.270 View mutations
520 S 15 4 19 0.248 0.734 View mutations
521 G 19 0 19 0.013 0.863 View mutations
522 A 19 0 19 0.027 0.882 View mutations
523 K 8 11 19 0.611 0.425 View mutations
524 L 19 0 19 0.006 0.899 View mutations
525 D 19 0 19 0.003 0.878 View mutations