O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
526 A 19 0 19 0.019 0.971 View mutations
527 A 19 0 19 0.001 0.975 View mutations
528 G 19 0 19 0.001 0.948 View mutations
529 L 19 0 19 0.041 0.912 View mutations
530 H 15 4 19 0.274 0.738 View mutations
531 H 11 8 19 0.413 0.562 View mutations
532 H 11 8 19 0.489 0.562 View mutations
533 R 2 17 19 0.884 0.167 View mutations
534 H 3 16 19 0.804 0.164 View mutations
535 V 6 13 19 0.700 0.323 View mutations
536 H 6 13 19 0.650 0.316 View mutations
537 H 16 3 19 0.199 0.839 View mutations
538 H 5 14 19 0.714 0.263 View mutations
539 V 6 13 19 0.663 0.318 View mutations
540 H 15 4 19 0.165 0.769 View mutations
541 H 19 0 19 0.017 0.977 View mutations
542 S 17 2 19 0.070 0.841 View mutations
543 T 19 0 19 0.010 0.936 View mutations
544 A 18 1 19 0.059 0.870 View mutations
545 R 19 0 19 0.001 0.872 View mutations
546 P 19 0 19 0.002 0.915 View mutations
547 K 19 0 19 0.074 0.848 View mutations
548 E 19 0 19 0.004 0.775 View mutations
549 Q 19 0 19 0.003 0.887 View mutations
550 V 18 1 19 0.059 0.858 View mutations