O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
551 E 6 13 19 0.644 0.348 View mutations
552 A 16 3 19 0.209 0.753 View mutations
553 E 2 17 19 0.753 0.220 View mutations
554 A 12 7 19 0.345 0.585 View mutations
555 T 18 1 19 0.049 0.864 View mutations
556 R 16 3 19 0.151 0.800 View mutations
557 R 14 5 19 0.239 0.654 View mutations
558 A 19 0 19 0.015 0.888 View mutations
559 Q 19 0 19 0.029 0.901 View mutations
560 S 19 0 19 0.013 0.913 View mutations
561 S 19 0 19 0.030 0.901 View mutations
562 F 17 2 19 0.150 0.795 View mutations
563 A 17 2 19 0.132 0.792 View mutations
564 W 2 17 19 0.899 0.218 View mutations
565 G 6 13 19 0.624 0.350 View mutations
566 L 18 1 19 0.091 0.807 View mutations
567 E 8 11 19 0.591 0.427 View mutations
568 P 17 2 19 0.112 0.758 View mutations
569 H 18 1 19 0.057 0.833 View mutations
570 S 19 0 19 0.048 0.902 View mutations
571 H 14 5 19 0.333 0.654 View mutations
572 G 12 7 19 0.389 0.581 View mutations
573 A 18 1 19 0.073 0.829 View mutations
574 R 18 1 19 0.030 0.751 View mutations
575 S 19 0 19 0.010 0.820 View mutations