O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
576 R 19 0 19 0.011 0.748 View mutations
577 G 19 0 19 0.051 0.875 View mutations
578 Y 19 0 19 0.000 0.763 View mutations
579 S 19 0 19 0.010 0.794 View mutations
580 E 16 3 19 0.147 0.642 View mutations
581 S 19 0 19 0.001 0.891 View mutations
582 V 19 0 19 0.025 0.909 View mutations
583 G 19 0 19 0.000 0.868 View mutations
584 A 19 0 19 0.001 0.974 View mutations
585 A 19 0 19 0.029 0.934 View mutations
586 P 19 0 19 0.007 0.944 View mutations
587 N 16 3 19 0.185 0.820 View mutations
588 A 18 1 19 0.056 0.916 View mutations
589 S 19 0 19 0.021 0.932 View mutations
590 D 19 0 19 0.005 0.828 View mutations
591 G 19 0 19 0.002 0.936 View mutations
592 L 16 3 19 0.147 0.761 View mutations
593 A 19 0 19 0.017 0.872 View mutations
594 H 19 0 19 0.028 0.875 View mutations
595 S 14 5 19 0.262 0.690 View mutations
596 G 9 10 19 0.490 0.467 View mutations
597 K 3 16 19 0.834 0.252 View mutations
598 V 12 7 19 0.408 0.581 View mutations
599 G 8 11 19 0.565 0.424 View mutations
600 V 16 3 19 0.166 0.765 View mutations