O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
601 A 17 2 19 0.184 0.728 View mutations
602 C 14 5 19 0.266 0.649 View mutations
603 K 1 18 19 0.924 0.242 View mutations
604 R 5 14 19 0.717 0.346 View mutations
605 N 6 13 19 0.614 0.354 View mutations
606 A 14 5 19 0.306 0.635 View mutations
607 K 18 1 19 0.076 0.689 View mutations
608 K 10 9 19 0.421 0.487 View mutations
609 A 19 0 19 0.006 0.772 View mutations
610 E 18 1 19 0.128 0.689 View mutations
611 S 12 7 19 0.301 0.585 View mutations
612 G 19 0 19 0.018 0.818 View mutations
613 K 19 0 19 0.005 0.852 View mutations
614 S 19 0 19 0.004 0.903 View mutations
615 A 19 0 19 0.006 0.962 View mutations
616 S 19 0 19 0.010 0.867 View mutations
617 T 19 0 19 0.022 0.868 View mutations
618 E 10 9 19 0.437 0.492 View mutations
619 V 19 0 19 0.004 0.812 View mutations
620 P 16 3 19 0.169 0.717 View mutations
621 G 11 8 19 0.415 0.543 View mutations
622 A 19 0 19 0.001 0.836 View mutations
623 S 19 0 19 0.021 0.820 View mutations
624 E 15 4 19 0.280 0.590 View mutations
625 D 1 18 19 0.893 0.250 View mutations