O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
626 A 18 1 19 0.055 0.704 View mutations
627 E 19 0 19 0.002 0.590 View mutations
628 K 2 17 19 0.793 0.335 View mutations
629 N 13 6 19 0.327 0.527 View mutations
630 Q 17 2 19 0.086 0.549 View mutations
631 K 1 18 19 0.953 0.366 View mutations
632 I 0 19 19 0.998 0.400 View mutations
633 M 3 16 19 0.834 0.371 View mutations
634 Q 3 16 19 0.840 0.382 View mutations
635 W 0 19 19 1.000 0.399 View mutations
636 I 1 18 19 0.968 0.410 View mutations
637 I 4 15 19 0.783 0.413 View mutations
638 E 1 18 19 0.954 0.406 View mutations
639 G 0 19 19 1.000 0.441 View mutations
640 E 0 19 19 1.000 0.375 View mutations
641 K 6 13 19 0.698 0.399 View mutations
642 E 15 4 19 0.317 0.554 View mutations
643 I 3 16 19 0.878 0.306 View mutations
644 S 18 1 19 0.078 0.659 View mutations
645 R 12 7 19 0.345 0.527 View mutations
646 H 19 0 19 0.028 0.695 View mutations
647 R 4 15 19 0.747 0.348 View mutations
648 R 3 16 19 0.768 0.336 View mutations
649 T 10 9 19 0.480 0.481 View mutations
650 G 12 7 19 0.377 0.536 View mutations