O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
651 H 11 8 19 0.447 0.516 View mutations
652 G 19 0 19 0.054 0.728 View mutations
653 S 19 0 19 0.002 0.879 View mutations
654 S 19 0 19 0.002 0.803 View mutations
655 G 19 0 19 0.001 0.738 View mutations
656 T 19 0 19 0.005 0.806 View mutations
657 R 19 0 19 0.041 0.767 View mutations
658 K 16 3 19 0.208 0.691 View mutations
659 P 18 1 19 0.053 0.816 View mutations
660 Q 18 1 19 0.089 0.835 View mutations
661 P 10 9 19 0.420 0.503 View mutations
662 H 19 0 19 0.002 0.798 View mutations
663 E 19 0 19 0.032 0.754 View mutations
664 N 18 1 19 0.055 0.851 View mutations
665 S 19 0 19 0.049 0.882 View mutations
666 R 16 3 19 0.166 0.715 View mutations
667 P 15 4 19 0.234 0.684 View mutations
668 L 17 2 19 0.126 0.756 View mutations
669 S 8 11 19 0.606 0.425 View mutations
670 L 19 0 19 0.017 0.837 View mutations
671 E 18 1 19 0.073 0.729 View mutations
672 H 5 14 19 0.682 0.317 View mutations
673 P 8 11 19 0.569 0.428 View mutations
674 W 1 18 19 0.902 0.207 View mutations
675 A 16 3 19 0.184 0.685 View mutations