O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
676 G 19 0 19 0.072 0.808 View mutations
677 P 19 0 19 0.009 0.760 View mutations
678 Q 11 8 19 0.455 0.516 View mutations
679 L 17 2 19 0.090 0.648 View mutations
680 R 18 1 19 0.057 0.704 View mutations
681 T 18 1 19 0.048 0.700 View mutations
682 S 19 0 19 0.015 0.753 View mutations
683 V 10 9 19 0.484 0.460 View mutations
684 Q 11 8 19 0.482 0.479 View mutations
685 P 0 19 19 1.000 0.353 View mutations
686 S 3 16 19 0.883 0.368 View mutations
687 H 2 17 19 0.882 0.397 View mutations
688 L 19 0 19 0.014 0.464 View mutations
689 F 13 6 19 0.311 0.458 View mutations
690 I 13 6 19 0.293 0.440 View mutations
691 Q 10 9 19 0.467 0.442 View mutations
692 D 1 18 19 0.950 0.460 View mutations
693 P 8 11 19 0.587 0.435 View mutations
694 T 4 15 19 0.722 0.405 View mutations
695 M 5 14 19 0.705 0.433 View mutations
696 P 6 13 19 0.708 0.443 View mutations
697 P 14 5 19 0.253 0.445 View mutations
698 H 19 0 19 0.004 0.460 View mutations
699 P 14 5 19 0.311 0.446 View mutations
700 A 16 3 19 0.153 0.394 View mutations