O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
701 P 19 0 19 0.001 0.382 View mutations
702 N 12 7 19 0.364 0.446 View mutations
703 P 13 6 19 0.325 0.411 View mutations
704 L 2 17 19 0.882 0.429 View mutations
705 T 2 17 19 0.896 0.434 View mutations
706 Q 10 9 19 0.458 0.432 View mutations
707 L 0 19 19 1.000 0.410 View mutations
708 E 1 18 19 0.950 0.442 View mutations
709 E 9 10 19 0.544 0.431 View mutations
710 A 11 8 19 0.437 0.449 View mutations
711 R 0 19 19 0.982 0.360 View mutations
712 R 13 6 19 0.382 0.471 View mutations
713 R 18 1 19 0.062 0.520 View mutations
714 L 8 11 19 0.564 0.433 View mutations
715 E 4 15 19 0.743 0.385 View mutations
716 E 19 0 19 0.001 0.593 View mutations
717 E 19 0 19 0.017 0.622 View mutations
718 E 8 11 19 0.538 0.429 View mutations
719 K 14 5 19 0.310 0.593 View mutations
720 R 16 3 19 0.196 0.630 View mutations
721 A 15 4 19 0.268 0.625 View mutations
722 S 8 11 19 0.582 0.428 View mutations
723 R 9 10 19 0.558 0.464 View mutations
724 A 17 2 19 0.101 0.663 View mutations
725 P 15 4 19 0.225 0.653 View mutations