O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
726 S 19 0 19 0.000 0.777 View mutations
727 K 19 0 19 0.017 0.701 View mutations
728 Q 19 0 19 0.000 0.699 View mutations
729 R 17 2 19 0.165 0.695 View mutations
730 Y 19 0 19 0.032 0.800 View mutations
731 V 19 0 19 0.001 0.777 View mutations
732 Q 17 2 19 0.157 0.762 View mutations
733 E 18 1 19 0.079 0.759 View mutations
734 V 15 4 19 0.232 0.666 View mutations
735 M 17 2 19 0.085 0.741 View mutations
736 R 19 0 19 0.001 0.842 View mutations
737 R 19 0 19 0.018 0.846 View mutations
738 G 16 3 19 0.147 0.694 View mutations
739 R 19 0 19 0.000 0.888 View mutations
740 A 12 7 19 0.385 0.600 View mutations
741 C 19 0 19 0.033 0.920 View mutations
742 V 19 0 19 0.001 0.845 View mutations
743 R 19 0 19 0.000 0.872 View mutations
744 P 19 0 19 0.000 0.873 View mutations
745 A 17 2 19 0.128 0.798 View mutations
746 C 19 0 19 0.018 0.904 View mutations
747 A 18 1 19 0.069 0.858 View mutations
748 P 17 2 19 0.150 0.773 View mutations
749 V 14 5 19 0.283 0.666 View mutations
750 L 19 0 19 0.005 0.852 View mutations