O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 K 1 18 19 0.958 0.637 View mutations
127 L 1 18 19 0.947 0.503 View mutations
128 E 1 18 19 0.910 0.393 View mutations
129 P 11 8 19 0.441 0.451 View mutations
130 C 0 19 19 0.939 0.256 View mutations
131 D 4 15 19 0.744 0.351 View mutations
132 S 3 16 19 0.860 0.345 View mutations
133 N 15 4 19 0.240 0.503 View mutations
134 E 5 14 19 0.757 0.502 View mutations
135 E 12 7 19 0.335 0.456 View mutations
136 K 7 12 19 0.650 0.513 View mutations
137 R 1 18 19 0.876 0.654 View mutations
138 L 3 16 19 0.757 0.596 View mutations
139 K 13 6 19 0.349 0.431 View mutations
140 L 4 15 19 0.790 0.645 View mutations
141 A 4 15 19 0.678 0.700 View mutations
142 R 18 1 19 0.030 0.264 View mutations
143 A 19 0 19 0.003 0.159 View mutations
144 I 18 1 19 0.205 0.143 View mutations
145 Y 19 0 19 0.003 0.196 View mutations
146 R 19 0 19 0.000 0.233 View mutations
147 K 14 5 19 0.277 0.350 View mutations
148 Y 19 0 19 0.020 0.158 View mutations
149 I 18 1 19 0.102 0.235 View mutations
150 L 19 0 19 0.015 0.347 View mutations