O15169 (AXIN1)

Overview
Predicted structure (AF):
AF-O15169-F1-model_v4
Uniprot entry:
O15169
Gene:
AXIN1
Protein length:
862 residues
Mutations found:
16377
Benign based on D2Deep prediction:
9368 out of 16377 mutations
Pathogenic based on D2Deep prediction:
7009 out of 16377 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 16377 mutations across 862 unique positions. There are 9368 benign and 7009 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 D 12 7 19 0.383 0.448 View mutations
152 N 2 17 19 0.894 0.610 View mutations
153 N 18 1 19 0.127 0.385 View mutations
154 G 7 12 19 0.612 0.574 View mutations
155 I 1 18 19 0.947 0.727 View mutations
156 V 2 17 19 0.914 0.686 View mutations
157 S 8 11 19 0.606 0.538 View mutations
158 R 0 19 19 0.946 0.710 View mutations
159 Q 3 16 19 0.846 0.626 View mutations
160 T 4 15 19 0.755 0.636 View mutations
161 K 0 19 19 0.997 0.787 View mutations
162 P 0 19 19 1.000 0.838 View mutations
163 A 0 19 19 0.996 0.883 View mutations
164 T 0 19 19 1.000 0.857 View mutations
165 K 3 16 19 0.872 0.686 View mutations
166 S 1 18 19 0.956 0.735 View mutations
167 F 1 18 19 0.921 0.745 View mutations
168 I 0 19 19 0.993 0.812 View mutations
169 K 14 5 19 0.364 0.450 View mutations
170 G 4 15 19 0.803 0.620 View mutations
171 C 3 16 19 0.841 0.580 View mutations
172 I 4 15 19 0.756 0.537 View mutations
173 M 18 1 19 0.045 0.380 View mutations
174 K 15 4 19 0.180 0.490 View mutations
175 Q 17 2 19 0.178 0.383 View mutations