O43543 (XRCC2)

Overview
Predicted structure (AF):
AF-O43543-F1-model_v4
Uniprot entry:
O43543
Gene:
XRCC2
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
2575 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2744 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 2575 benign and 2744 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 L 12 7 19 0.387 0.433 View mutations
127 L 3 16 19 0.746 0.667 View mutations
128 L 1 18 19 0.925 0.686 View mutations
129 T 17 2 19 0.171 0.324 View mutations
130 L 0 19 19 0.946 0.791 View mutations
131 Y 1 18 19 0.945 0.538 View mutations
132 S 0 19 19 0.997 0.605 View mutations
133 L 9 10 19 0.566 0.506 View mutations
134 E 0 19 19 0.997 0.642 View mutations
135 S 16 3 19 0.165 0.489 View mutations
136 M 5 14 19 0.686 0.438 View mutations
137 F 4 15 19 0.799 0.550 View mutations
138 C 12 7 19 0.317 0.406 View mutations
139 S 14 5 19 0.254 0.436 View mutations
140 H 10 9 19 0.482 0.498 View mutations
141 P 16 3 19 0.251 0.339 View mutations
142 S 19 0 19 0.040 0.409 View mutations
143 L 19 0 19 0.011 0.403 View mutations
144 C 18 1 19 0.059 0.414 View mutations
145 L 5 14 19 0.705 0.572 View mutations
146 L 19 0 19 0.003 0.327 View mutations
147 I 6 13 19 0.649 0.531 View mutations
148 L 19 0 19 0.001 0.300 View mutations
149 D 14 5 19 0.375 0.327 View mutations
150 S 17 2 19 0.144 0.236 View mutations