O43543 (XRCC2)

Overview
Predicted structure (AF):
AF-O43543-F1-model_v4
Uniprot entry:
O43543
Gene:
XRCC2
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
2575 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2744 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 2575 benign and 2744 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 L 9 10 19 0.512 0.517 View mutations
152 S 0 19 19 1.000 0.940 View mutations
153 A 7 12 19 0.669 0.624 View mutations
154 F 0 19 19 0.951 0.922 View mutations
155 Y 0 19 19 0.998 0.911 View mutations
156 W 0 19 19 0.997 0.936 View mutations
157 I 7 12 19 0.628 0.585 View mutations
158 D 1 18 19 0.964 0.780 View mutations
159 R 1 18 19 0.947 0.715 View mutations
160 V 11 8 19 0.402 0.489 View mutations
161 N 6 13 19 0.700 0.513 View mutations
162 G 0 19 19 1.000 0.689 View mutations
163 G 0 19 19 0.999 0.694 View mutations
164 E 2 17 19 0.828 0.575 View mutations
165 S 17 2 19 0.184 0.491 View mutations
166 V 10 9 19 0.430 0.500 View mutations
167 N 19 0 19 0.005 0.580 View mutations
168 L 17 2 19 0.151 0.470 View mutations
169 Q 18 1 19 0.148 0.366 View mutations
170 E 9 10 19 0.423 0.506 View mutations
171 S 11 8 19 0.381 0.459 View mutations
172 T 19 0 19 0.031 0.436 View mutations
173 L 19 0 19 0.010 0.263 View mutations
174 R 19 0 19 0.022 0.384 View mutations
175 K 15 4 19 0.227 0.396 View mutations