O43543 (XRCC2)

Overview
Predicted structure (AF):
AF-O43543-F1-model_v4
Uniprot entry:
O43543
Gene:
XRCC2
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
2575 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2744 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5319 mutations across 280 unique positions. There are 2575 benign and 2744 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 C 9 10 19 0.577 0.508 View mutations
177 S 6 13 19 0.682 0.518 View mutations
178 Q 19 0 19 0.017 0.550 View mutations
179 C 15 4 19 0.231 0.443 View mutations
180 L 12 7 19 0.405 0.463 View mutations
181 E 19 0 19 0.008 0.393 View mutations
182 K 19 0 19 0.055 0.466 View mutations
183 L 4 15 19 0.722 0.514 View mutations
184 V 13 6 19 0.318 0.479 View mutations
185 N 18 1 19 0.039 0.516 View mutations
186 D 19 0 19 0.084 0.492 View mutations
187 Y 3 16 19 0.829 0.533 View mutations
188 R 14 5 19 0.353 0.495 View mutations
189 L 1 18 19 0.947 0.530 View mutations
190 V 10 9 19 0.493 0.422 View mutations
191 L 2 17 19 0.915 0.551 View mutations
192 F 6 13 19 0.555 0.514 View mutations
193 A 1 18 19 0.918 0.672 View mutations
194 T 4 15 19 0.807 0.604 View mutations
195 T 0 19 19 0.936 0.766 View mutations
196 Q 16 3 19 0.158 0.389 View mutations
197 T 18 1 19 0.100 0.403 View mutations
198 I 9 10 19 0.519 0.505 View mutations
199 M 7 12 19 0.498 0.508 View mutations
200 Q 2 17 19 0.850 0.400 View mutations