O43543 (XRCC2)

Overview
Predicted structure (AF):
AF-O43543-F1-model_v4
Uniprot entry:
O43543
Gene:
XRCC2
Protein length:
280 residues
Mutations found:
5319
Benign based on D2Deep prediction:
2575 out of 5319 mutations
Pathogenic based on D2Deep prediction:
2744 out of 5319 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5319 mutations across 280 unique positions. There are 2575 benign and 2744 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 K 7 12 19 0.535 0.407 View mutations
202 A 18 1 19 0.073 0.659 View mutations
203 S 19 0 19 0.003 0.736 View mutations
204 S 19 0 19 0.008 0.814 View mutations
205 S 19 0 19 0.047 0.846 View mutations
206 S 19 0 19 0.058 0.844 View mutations
207 E 17 2 19 0.138 0.722 View mutations
208 E 19 0 19 0.006 0.874 View mutations
209 P 19 0 19 0.007 0.919 View mutations
210 S 19 0 19 0.004 0.965 View mutations
211 H 19 0 19 0.003 1.000 View mutations
212 A 10 9 19 0.488 0.515 View mutations
213 S 17 2 19 0.095 0.878 View mutations
214 R 16 3 19 0.261 0.824 View mutations
215 R 19 0 19 0.004 0.934 View mutations
216 L 19 0 19 0.026 0.929 View mutations
217 C 19 0 19 0.006 0.917 View mutations
218 D 16 3 19 0.236 0.670 View mutations
219 V 19 0 19 0.024 0.729 View mutations
220 D 19 0 19 0.026 0.620 View mutations
221 I 19 0 19 0.000 0.646 View mutations
222 D 17 2 19 0.176 0.408 View mutations
223 Y 19 0 19 0.000 0.498 View mutations
224 R 1 18 19 0.913 0.601 View mutations
225 P 14 5 19 0.249 0.401 View mutations