O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 V 8 11 19 0.564 0.508 View mutations
227 G 19 0 19 0.040 0.357 View mutations
228 G 6 13 19 0.631 0.557 View mutations
229 E 1 18 19 0.967 0.544 View mutations
230 F 1 18 19 0.927 0.523 View mutations
231 Y 1 18 19 0.932 0.532 View mutations
232 T 6 13 19 0.665 0.501 View mutations
233 P 0 19 19 1.000 0.548 View mutations
234 S 1 18 19 0.925 0.468 View mutations
235 K 10 9 19 0.489 0.428 View mutations
236 F 6 13 19 0.698 0.445 View mutations
237 E 0 19 19 0.997 0.468 View mutations
238 D 1 18 19 0.951 0.418 View mutations
239 S 7 12 19 0.597 0.406 View mutations
240 G 12 7 19 0.367 0.506 View mutations
241 S 19 0 19 0.027 0.611 View mutations
242 G 19 0 19 0.038 0.552 View mutations
243 K 19 0 19 0.006 0.404 View mutations
244 N 19 0 19 0.000 0.498 View mutations
245 K 19 0 19 0.051 0.561 View mutations
246 A 16 3 19 0.138 0.571 View mutations
247 R 19 0 19 0.002 0.653 View mutations
248 S 16 3 19 0.218 0.623 View mutations
249 S 13 6 19 0.312 0.574 View mutations
250 S 13 6 19 0.355 0.601 View mutations