O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 G 9 10 19 0.529 0.449 View mutations
202 A 19 0 19 0.001 0.440 View mutations
203 R 18 1 19 0.042 0.528 View mutations
204 G 19 0 19 0.045 0.483 View mutations
205 A 3 16 19 0.834 0.520 View mutations
206 V 1 18 19 0.920 0.553 View mutations
207 E 1 18 19 0.926 0.609 View mutations
208 G 1 18 19 0.964 0.606 View mutations
209 I 10 9 19 0.464 0.496 View mutations
210 L 6 13 19 0.690 0.546 View mutations
211 I 3 16 19 0.837 0.561 View mutations
212 Q 1 18 19 0.964 0.574 View mutations
213 Q 0 19 19 0.996 0.608 View mutations
214 V 0 19 19 0.989 0.664 View mutations
215 F 6 13 19 0.631 0.530 View mutations
216 E 1 18 19 0.931 0.590 View mutations
217 S 11 8 19 0.474 0.482 View mutations
218 G 11 8 19 0.406 0.483 View mutations
219 G 15 4 19 0.259 0.481 View mutations
220 S 19 0 19 0.023 0.401 View mutations
221 K 19 0 19 0.001 0.428 View mutations
222 K 18 1 19 0.124 0.451 View mutations
223 C 19 0 19 0.006 0.427 View mutations
224 I 5 14 19 0.690 0.529 View mutations
225 Q 17 2 19 0.149 0.434 View mutations