O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 P 19 0 19 0.005 0.546 View mutations
177 L 13 6 19 0.265 0.447 View mutations
178 G 19 0 19 0.019 0.403 View mutations
179 N 19 0 19 0.023 0.475 View mutations
180 G 19 0 19 0.034 0.389 View mutations
181 I 19 0 19 0.019 0.406 View mutations
182 Q 17 2 19 0.184 0.528 View mutations
183 T 18 1 19 0.159 0.463 View mutations
184 M 17 2 19 0.125 0.447 View mutations
185 S 19 0 19 0.012 0.396 View mutations
186 A 17 2 19 0.110 0.499 View mutations
187 S 17 2 19 0.154 0.490 View mutations
188 V 13 6 19 0.326 0.402 View mutations
189 Q 4 15 19 0.762 0.443 View mutations
190 R 4 15 19 0.777 0.416 View mutations
191 A 6 13 19 0.658 0.423 View mutations
192 V 7 12 19 0.585 0.434 View mutations
193 A 8 11 19 0.600 0.433 View mutations
194 M 8 11 19 0.517 0.435 View mutations
195 S 9 10 19 0.479 0.443 View mutations
196 S 17 2 19 0.137 0.507 View mutations
197 G 11 8 19 0.420 0.473 View mutations
198 D 3 16 19 0.829 0.389 View mutations
199 V 7 12 19 0.623 0.418 View mutations
200 P 6 13 19 0.676 0.403 View mutations