O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 Q 12 7 19 0.416 0.596 View mutations
277 G 19 0 19 0.021 0.856 View mutations
278 S 19 0 19 0.009 0.909 View mutations
279 V 15 4 19 0.178 0.666 View mutations
280 P 17 2 19 0.111 0.822 View mutations
281 A 15 4 19 0.249 0.708 View mutations
282 P 19 0 19 0.011 0.843 View mutations
283 L 19 0 19 0.014 0.877 View mutations
284 A 18 1 19 0.137 0.721 View mutations
285 L 17 2 19 0.096 0.634 View mutations
286 P 19 0 19 0.000 0.741 View mutations
287 S 19 0 19 0.008 0.763 View mutations
288 D 7 12 19 0.643 0.416 View mutations
289 P 16 3 19 0.182 0.612 View mutations
290 Q 12 7 19 0.409 0.517 View mutations
291 L 11 8 19 0.390 0.462 View mutations
292 H 12 7 19 0.442 0.472 View mutations
293 Q 19 0 19 0.029 0.442 View mutations
294 K 9 10 19 0.471 0.500 View mutations
295 N 18 1 19 0.070 0.377 View mutations
296 E 14 5 19 0.266 0.426 View mutations
297 D 0 19 19 1.000 0.706 View mutations
298 E 0 19 19 0.982 0.708 View mutations
299 C 0 19 19 1.000 0.772 View mutations
300 A 0 19 19 0.978 0.682 View mutations