O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 G 15 4 19 0.224 0.684 View mutations
252 P 17 2 19 0.111 0.662 View mutations
253 K 7 12 19 0.606 0.405 View mutations
254 P 16 3 19 0.178 0.690 View mutations
255 L 14 5 19 0.269 0.596 View mutations
256 V 18 1 19 0.107 0.664 View mutations
257 R 10 9 19 0.468 0.483 View mutations
258 A 17 2 19 0.188 0.681 View mutations
259 K 16 3 19 0.220 0.670 View mutations
260 G 15 4 19 0.223 0.678 View mutations
261 A 16 3 19 0.174 0.751 View mutations
262 Q 3 16 19 0.854 0.212 View mutations
263 G 15 4 19 0.239 0.769 View mutations
264 A 14 5 19 0.224 0.737 View mutations
265 A 18 1 19 0.075 0.865 View mutations
266 P 19 0 19 0.004 0.956 View mutations
267 G 13 6 19 0.396 0.662 View mutations
268 G 18 1 19 0.063 0.924 View mutations
269 G 18 1 19 0.116 0.901 View mutations
270 E 11 8 19 0.402 0.553 View mutations
271 A 15 4 19 0.220 0.749 View mutations
272 R 19 0 19 0.000 0.974 View mutations
273 L 19 0 19 0.037 0.864 View mutations
274 G 17 2 19 0.190 0.748 View mutations
275 Q 18 1 19 0.040 0.840 View mutations