O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 V 15 4 19 0.221 0.396 View mutations
302 C 0 19 19 0.991 0.722 View mutations
303 R 3 16 19 0.828 0.595 View mutations
304 D 9 10 19 0.561 0.517 View mutations
305 G 19 0 19 0.004 0.216 View mutations
306 G 14 5 19 0.275 0.325 View mutations
307 E 6 13 19 0.619 0.626 View mutations
308 L 15 4 19 0.197 0.284 View mutations
309 I 14 5 19 0.242 0.363 View mutations
310 C 18 1 19 0.084 0.227 View mutations
311 C 1 18 19 0.912 0.799 View mutations
312 D 19 0 19 0.039 0.159 View mutations
313 G 18 1 19 0.158 0.208 View mutations
314 C 0 19 19 1.000 0.825 View mutations
315 P 0 19 19 0.985 0.868 View mutations
316 R 3 16 19 0.815 0.646 View mutations
317 A 0 19 19 0.996 0.878 View mutations
318 F 7 12 19 0.544 0.579 View mutations
319 H 16 3 19 0.201 0.334 View mutations
320 L 14 5 19 0.293 0.357 View mutations
321 A 7 12 19 0.627 0.568 View mutations
322 C 0 19 19 0.999 0.744 View mutations
323 L 8 11 19 0.608 0.535 View mutations
324 S 2 17 19 0.914 0.546 View mutations
325 P 0 19 19 1.000 0.703 View mutations