O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 P 0 19 19 1.000 0.708 View mutations
327 L 2 17 19 0.874 0.681 View mutations
328 R 11 8 19 0.411 0.437 View mutations
329 E 18 1 19 0.146 0.438 View mutations
330 I 3 16 19 0.834 0.651 View mutations
331 P 0 19 19 1.000 0.715 View mutations
332 S 0 19 19 0.995 0.663 View mutations
333 G 0 19 19 1.000 0.672 View mutations
334 T 3 16 19 0.832 0.583 View mutations
335 W 0 19 19 0.995 0.624 View mutations
336 R 15 4 19 0.270 0.414 View mutations
337 C 16 3 19 0.242 0.407 View mutations
338 S 19 0 19 0.005 0.370 View mutations
339 S 19 0 19 0.000 0.402 View mutations
340 C 7 12 19 0.651 0.505 View mutations
341 L 18 1 19 0.048 0.378 View mutations
342 Q 11 8 19 0.392 0.457 View mutations
343 A 9 10 19 0.524 0.443 View mutations
344 T 7 12 19 0.627 0.412 View mutations
345 V 19 0 19 0.011 0.644 View mutations
346 Q 19 0 19 0.008 0.735 View mutations
347 E 14 5 19 0.389 0.617 View mutations
348 V 18 1 19 0.142 0.697 View mutations
349 Q 18 1 19 0.049 0.695 View mutations
350 P 19 0 19 0.000 0.735 View mutations