O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 R 19 0 19 0.009 0.798 View mutations
352 A 18 1 19 0.056 0.660 View mutations
353 E 11 8 19 0.360 0.512 View mutations
354 E 19 0 19 0.073 0.780 View mutations
355 P 19 0 19 0.011 0.818 View mutations
356 R 19 0 19 0.000 0.840 View mutations
357 P 16 3 19 0.135 0.682 View mutations
358 Q 8 11 19 0.549 0.425 View mutations
359 E 12 7 19 0.419 0.549 View mutations
360 P 19 0 19 0.008 0.768 View mutations
361 P 18 1 19 0.093 0.765 View mutations
362 V 14 5 19 0.303 0.619 View mutations
363 E 4 15 19 0.786 0.315 View mutations
364 T 15 4 19 0.282 0.663 View mutations
365 P 17 2 19 0.132 0.761 View mutations
366 L 17 2 19 0.133 0.737 View mutations
367 P 17 2 19 0.133 0.781 View mutations
368 P 8 11 19 0.595 0.424 View mutations
369 G 19 0 19 0.034 0.737 View mutations
370 L 19 0 19 0.025 0.803 View mutations
371 R 18 1 19 0.088 0.886 View mutations
372 S 19 0 19 0.000 0.879 View mutations
373 A 11 8 19 0.396 0.545 View mutations
374 G 17 2 19 0.119 0.769 View mutations
375 E 18 1 19 0.101 0.770 View mutations