O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
376 E 19 0 19 0.015 0.864 View mutations
377 V 19 0 19 0.010 0.879 View mutations
378 R 15 4 19 0.217 0.759 View mutations
379 G 6 13 19 0.712 0.347 View mutations
380 P 8 11 19 0.533 0.424 View mutations
381 P 17 2 19 0.110 0.879 View mutations
382 G 16 3 19 0.244 0.821 View mutations
383 E 13 6 19 0.411 0.611 View mutations
384 P 17 2 19 0.134 0.840 View mutations
385 L 19 0 19 0.001 0.934 View mutations
386 A 19 0 19 0.017 0.943 View mutations
387 G 19 0 19 0.014 0.860 View mutations
388 M 18 1 19 0.048 0.877 View mutations
389 D 19 0 19 0.050 0.830 View mutations
390 T 18 1 19 0.052 0.810 View mutations
391 T 19 0 19 0.038 0.803 View mutations
392 L 18 1 19 0.061 0.773 View mutations
393 V 19 0 19 0.002 0.805 View mutations
394 Y 19 0 19 0.026 0.807 View mutations
395 K 19 0 19 0.000 0.822 View mutations
396 H 19 0 19 0.000 0.824 View mutations
397 L 19 0 19 0.027 0.790 View mutations
398 P 17 2 19 0.146 0.733 View mutations
399 A 19 0 19 0.002 0.790 View mutations
400 P 19 0 19 0.031 0.881 View mutations