O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 P 18 1 19 0.069 0.843 View mutations
402 S 19 0 19 0.001 0.882 View mutations
403 A 19 0 19 0.000 0.859 View mutations
404 A 15 4 19 0.200 0.697 View mutations
405 P 19 0 19 0.001 0.879 View mutations
406 L 19 0 19 0.001 0.794 View mutations
407 P 18 1 19 0.054 0.860 View mutations
408 G 13 6 19 0.335 0.607 View mutations
409 L 18 1 19 0.092 0.721 View mutations
410 D 18 1 19 0.068 0.750 View mutations
411 S 18 1 19 0.061 0.765 View mutations
412 S 6 13 19 0.707 0.355 View mutations
413 A 13 6 19 0.346 0.543 View mutations
414 L 18 1 19 0.073 0.692 View mutations
415 H 18 1 19 0.048 0.737 View mutations
416 P 8 11 19 0.620 0.428 View mutations
417 L 16 3 19 0.194 0.604 View mutations
418 L 17 2 19 0.102 0.655 View mutations
419 C 18 1 19 0.084 0.731 View mutations
420 V 9 10 19 0.538 0.454 View mutations
421 G 19 0 19 0.004 0.748 View mutations
422 P 19 0 19 0.003 0.771 View mutations
423 E 7 12 19 0.588 0.399 View mutations
424 G 18 1 19 0.118 0.681 View mutations
425 Q 19 0 19 0.000 0.797 View mutations