O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 P 11 8 19 0.381 0.473 View mutations
127 R 14 5 19 0.288 0.526 View mutations
128 L 3 16 19 0.789 0.405 View mutations
129 P 2 17 19 0.843 0.420 View mutations
130 T 4 15 19 0.768 0.425 View mutations
131 K 0 19 19 0.999 0.433 View mutations
132 R 1 18 19 0.924 0.410 View mutations
133 K 2 17 19 0.879 0.457 View mutations
134 A 13 6 19 0.316 0.497 View mutations
135 S 17 2 19 0.093 0.473 View mutations
136 E 12 7 19 0.380 0.408 View mutations
137 E 6 13 19 0.692 0.501 View mutations
138 A 18 1 19 0.084 0.512 View mutations
139 R 18 1 19 0.081 0.577 View mutations
140 A 16 3 19 0.170 0.598 View mutations
141 A 19 0 19 0.010 0.627 View mutations
142 A 19 0 19 0.000 0.673 View mutations
143 P 3 16 19 0.750 0.319 View mutations
144 A 18 1 19 0.111 0.571 View mutations
145 A 19 0 19 0.006 0.545 View mutations
146 L 19 0 19 0.003 0.651 View mutations
147 T 18 1 19 0.080 0.644 View mutations
148 P 19 0 19 0.000 0.588 View mutations
149 R 19 0 19 0.006 0.645 View mutations
150 G 19 0 19 0.000 0.569 View mutations