O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 T 15 4 19 0.258 0.547 View mutations
152 A 15 4 19 0.196 0.545 View mutations
153 S 19 0 19 0.002 0.578 View mutations
154 P 19 0 19 0.000 0.594 View mutations
155 G 14 5 19 0.294 0.494 View mutations
156 S 19 0 19 0.010 0.611 View mutations
157 Q 19 0 19 0.008 0.705 View mutations
158 L 19 0 19 0.035 0.767 View mutations
159 K 5 14 19 0.689 0.365 View mutations
160 A 18 1 19 0.075 0.679 View mutations
161 K 8 11 19 0.606 0.428 View mutations
162 P 12 7 19 0.445 0.527 View mutations
163 P 17 2 19 0.140 0.701 View mutations
164 K 19 0 19 0.012 0.692 View mutations
165 K 19 0 19 0.001 0.572 View mutations
166 P 18 1 19 0.090 0.667 View mutations
167 E 17 2 19 0.120 0.558 View mutations
168 S 17 2 19 0.147 0.626 View mutations
169 S 18 1 19 0.050 0.708 View mutations
170 A 19 0 19 0.002 0.696 View mutations
171 E 8 11 19 0.596 0.431 View mutations
172 Q 18 1 19 0.048 0.577 View mutations
173 Q 18 1 19 0.087 0.594 View mutations
174 R 19 0 19 0.001 0.622 View mutations
175 L 18 1 19 0.087 0.519 View mutations