O75204 (TMEM127)

Overview
Predicted structure (AF):
AF-O75204-F1-model_v4
Uniprot entry:
O75204
Gene:
TMEM127
Protein length:
238 residues
Mutations found:
4521
Benign based on D2Deep prediction:
2714 out of 4521 mutations
Pathogenic based on D2Deep prediction:
1807 out of 4521 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4521 mutations across 238 unique positions. There are 2714 benign and 1807 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 H 10 9 19 0.458 0.465 View mutations
77 P 15 4 19 0.258 0.516 View mutations
78 D 6 13 19 0.647 0.397 View mutations
79 L 5 14 19 0.746 0.398 View mutations
80 L 4 15 19 0.758 0.374 View mutations
81 K 3 16 19 0.770 0.340 View mutations
82 D 7 12 19 0.596 0.423 View mutations
83 F 19 0 19 0.018 0.535 View mutations
84 C 8 11 19 0.510 0.432 View mutations
85 M 19 0 19 0.011 0.477 View mutations
86 N 19 0 19 0.006 0.536 View mutations
87 P 19 0 19 0.007 0.487 View mutations
88 Q 19 0 19 0.027 0.482 View mutations
89 T 19 0 19 0.029 0.416 View mutations
90 V 19 0 19 0.021 0.483 View mutations
91 L 15 4 19 0.224 0.403 View mutations
92 L 18 1 19 0.079 0.407 View mutations
93 L 18 1 19 0.056 0.484 View mutations
94 R 19 0 19 0.017 0.394 View mutations
95 V 14 5 19 0.292 0.417 View mutations
96 I 18 1 19 0.134 0.432 View mutations
97 A 19 0 19 0.056 0.472 View mutations
98 A 19 0 19 0.041 0.391 View mutations
99 F 19 0 19 0.079 0.417 View mutations
100 C 17 2 19 0.232 0.380 View mutations