O75204 (TMEM127)

Overview
Predicted structure (AF):
AF-O75204-F1-model_v4
Uniprot entry:
O75204
Gene:
TMEM127
Protein length:
238 residues
Mutations found:
4521
Benign based on D2Deep prediction:
2714 out of 4521 mutations
Pathogenic based on D2Deep prediction:
1807 out of 4521 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4521 mutations across 238 unique positions. There are 2714 benign and 1807 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 F 19 0 19 0.021 0.478 View mutations
102 L 19 0 19 0.005 0.410 View mutations
103 G 6 13 19 0.615 0.560 View mutations
104 I 14 5 19 0.378 0.462 View mutations
105 L 15 4 19 0.307 0.400 View mutations
106 C 18 1 19 0.149 0.404 View mutations
107 S 12 7 19 0.399 0.455 View mutations
108 L 13 6 19 0.292 0.459 View mutations
109 S 19 0 19 0.034 0.373 View mutations
110 A 4 15 19 0.766 0.621 View mutations
111 F 6 13 19 0.632 0.594 View mutations
112 L 19 0 19 0.016 0.241 View mutations
113 L 9 10 19 0.450 0.512 View mutations
114 D 0 19 19 0.993 0.852 View mutations
115 V 13 6 19 0.308 0.364 View mutations
116 F 16 3 19 0.183 0.292 View mutations
117 G 1 18 19 0.800 0.801 View mutations
118 P 9 10 19 0.513 0.511 View mutations
119 K 6 13 19 0.647 0.546 View mutations
120 H 8 11 19 0.567 0.532 View mutations
121 P 0 19 19 0.918 0.754 View mutations
122 A 6 13 19 0.606 0.591 View mutations
123 L 2 17 19 0.805 0.705 View mutations
124 K 7 12 19 0.609 0.547 View mutations
125 I 1 18 19 0.851 0.657 View mutations