O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 I 15 4 19 0.182 0.521 View mutations
227 F 19 0 19 0.000 0.400 View mutations
228 Q 19 0 19 0.006 0.483 View mutations
229 E 14 5 19 0.262 0.599 View mutations
230 I 19 0 19 0.006 0.711 View mutations
231 Y 19 0 19 0.003 0.374 View mutations
232 D 19 0 19 0.037 0.634 View mutations
233 K 19 0 19 0.037 0.865 View mutations
234 Q 18 1 19 0.130 0.750 View mutations
235 Y 19 0 19 0.031 0.619 View mutations
236 K 19 0 19 0.000 0.731 View mutations
237 S 19 0 19 0.008 0.763 View mutations
238 Q 16 3 19 0.149 0.703 View mutations
239 F 2 17 19 0.908 0.441 View mutations
240 E 19 0 19 0.000 0.734 View mutations
241 A 19 0 19 0.000 0.775 View mutations
242 Q 19 0 19 0.003 0.644 View mutations
243 K 19 0 19 0.001 0.523 View mutations
244 I 19 0 19 0.000 0.357 View mutations
245 W 19 0 19 0.043 0.517 View mutations
246 Y 2 17 19 0.905 0.616 View mutations
247 E 19 0 19 0.046 0.393 View mutations
248 H 0 19 19 1.000 0.716 View mutations
249 R 0 19 19 1.000 0.711 View mutations
250 L 0 19 19 1.000 0.820 View mutations