O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 V 1 18 19 0.961 0.784 View mutations
277 Q 9 10 19 0.558 0.508 View mutations
278 S 12 7 19 0.369 0.427 View mutations
279 D 0 19 19 0.994 0.765 View mutations
280 S 10 9 19 0.519 0.499 View mutations
281 V 2 17 19 0.896 0.640 View mutations
282 A 0 19 19 0.985 0.801 View mutations
283 Q 0 19 19 0.992 0.802 View mutations
284 G 0 19 19 1.000 0.738 View mutations
285 Y 1 18 19 0.947 0.699 View mutations
286 G 19 0 19 0.001 0.038 View mutations
287 S 2 17 19 0.910 0.762 View mutations
288 L 0 19 19 1.000 0.831 View mutations
289 G 13 6 19 0.323 0.400 View mutations
290 M 1 18 19 0.947 0.720 View mutations
291 M 0 19 19 1.000 0.756 View mutations
292 T 0 19 19 1.000 0.717 View mutations
293 S 17 2 19 0.125 0.287 View mutations
294 V 2 17 19 0.812 0.563 View mutations
295 L 19 0 19 0.001 0.249 View mutations
296 V 19 0 19 0.008 0.463 View mutations
297 C 5 14 19 0.729 0.448 View mutations
298 P 16 3 19 0.150 0.385 View mutations
299 D 8 11 19 0.587 0.431 View mutations
300 G 8 11 19 0.608 0.515 View mutations