O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 G 18 1 19 0.064 0.598 View mutations
177 G 3 16 19 0.784 0.456 View mutations
178 V 7 12 19 0.605 0.441 View mutations
179 A 15 4 19 0.196 0.499 View mutations
180 M 7 12 19 0.591 0.428 View mutations
181 G 15 4 19 0.223 0.435 View mutations
182 M 10 9 19 0.437 0.421 View mutations
183 Y 15 4 19 0.218 0.410 View mutations
184 N 4 15 19 0.785 0.510 View mutations
185 Q 19 0 19 0.001 0.481 View mutations
186 D 19 0 19 0.025 0.557 View mutations
187 K 19 0 19 0.003 0.610 View mutations
188 S 10 9 19 0.459 0.495 View mutations
189 I 1 18 19 0.907 0.629 View mutations
190 E 19 0 19 0.002 0.643 View mutations
191 D 11 8 19 0.394 0.438 View mutations
192 F 3 16 19 0.828 0.601 View mutations
193 A 15 4 19 0.196 0.474 View mutations
194 H 18 1 19 0.059 0.683 View mutations
195 S 15 4 19 0.225 0.424 View mutations
196 S 19 0 19 0.002 0.483 View mutations
197 F 19 0 19 0.068 0.478 View mutations
198 Q 19 0 19 0.018 0.785 View mutations
199 M 19 0 19 0.001 0.570 View mutations
200 A 2 17 19 0.907 0.415 View mutations