O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 L 18 1 19 0.104 0.513 View mutations
202 S 19 0 19 0.011 0.721 View mutations
203 K 19 0 19 0.005 0.699 View mutations
204 G 19 0 19 0.000 0.640 View mutations
205 W 6 13 19 0.714 0.399 View mutations
206 P 3 16 19 0.837 0.453 View mutations
207 L 2 17 19 0.850 0.455 View mutations
208 Y 6 13 19 0.648 0.504 View mutations
209 L 6 13 19 0.623 0.526 View mutations
210 S 16 3 19 0.186 0.434 View mutations
211 T 1 18 19 0.934 0.663 View mutations
212 K 0 19 19 1.000 0.764 View mutations
213 N 0 19 19 0.999 0.705 View mutations
214 T 0 19 19 1.000 0.775 View mutations
215 I 1 18 19 0.943 0.714 View mutations
216 L 0 19 19 0.998 0.661 View mutations
217 K 0 19 19 0.931 0.627 View mutations
218 K 9 10 19 0.485 0.436 View mutations
219 Y 6 13 19 0.653 0.560 View mutations
220 D 19 0 19 0.010 0.291 View mutations
221 G 18 1 19 0.059 0.397 View mutations
222 R 19 0 19 0.022 0.485 View mutations
223 F 19 0 19 0.001 0.368 View mutations
224 K 18 1 19 0.061 0.461 View mutations
225 D 19 0 19 0.004 0.410 View mutations