O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 I 0 19 19 1.000 0.799 View mutations
252 D 0 19 19 0.996 0.737 View mutations
253 D 0 19 19 1.000 0.726 View mutations
254 M 10 9 19 0.546 0.496 View mutations
255 V 3 16 19 0.771 0.580 View mutations
256 A 0 19 19 0.994 0.668 View mutations
257 Q 1 18 19 0.885 0.400 View mutations
258 A 10 9 19 0.464 0.438 View mutations
259 M 4 15 19 0.729 0.520 View mutations
260 K 14 5 19 0.275 0.391 View mutations
261 S 6 13 19 0.652 0.449 View mutations
262 E 5 14 19 0.719 0.421 View mutations
263 G 19 0 19 0.084 0.326 View mutations
264 G 12 7 19 0.424 0.482 View mutations
265 F 19 0 19 0.001 0.410 View mutations
266 I 12 7 19 0.314 0.460 View mutations
267 W 0 19 19 1.000 0.736 View mutations
268 A 1 18 19 0.929 0.731 View mutations
269 C 1 18 19 0.948 0.713 View mutations
270 K 0 19 19 1.000 0.779 View mutations
271 N 0 19 19 1.000 0.912 View mutations
272 Y 1 18 19 0.951 0.894 View mutations
273 D 3 16 19 0.837 0.784 View mutations
274 G 0 19 19 1.000 0.968 View mutations
275 D 19 0 19 0.003 0.000 View mutations