O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 K 19 0 19 0.020 0.585 View mutations
127 P 0 19 19 0.992 0.615 View mutations
128 I 0 19 19 1.000 0.659 View mutations
129 I 11 8 19 0.468 0.498 View mutations
130 I 1 18 19 0.948 0.645 View mutations
131 G 0 19 19 1.000 0.699 View mutations
132 R 0 19 19 1.000 0.785 View mutations
133 H 0 19 19 1.000 0.745 View mutations
134 A 0 19 19 0.994 0.789 View mutations
135 Y 6 13 19 0.653 0.556 View mutations
136 G 2 17 19 0.895 0.752 View mutations
137 D 0 19 19 0.986 0.782 View mutations
138 Q 2 17 19 0.869 0.625 View mutations
139 Y 0 19 19 0.980 0.605 View mutations
140 R 2 17 19 0.782 0.411 View mutations
141 A 9 10 19 0.500 0.500 View mutations
142 T 19 0 19 0.028 0.493 View mutations
143 D 19 0 19 0.000 0.454 View mutations
144 F 19 0 19 0.061 0.562 View mutations
145 V 19 0 19 0.000 0.699 View mutations
146 V 19 0 19 0.000 0.550 View mutations
147 P 17 2 19 0.122 0.625 View mutations
148 G 19 0 19 0.000 0.763 View mutations
149 P 19 0 19 0.002 0.697 View mutations
150 G 19 0 19 0.000 0.504 View mutations