O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 K 19 0 19 0.002 0.806 View mutations
152 V 8 11 19 0.582 0.433 View mutations
153 E 17 2 19 0.115 0.803 View mutations
154 I 19 0 19 0.022 0.498 View mutations
155 T 18 1 19 0.036 0.806 View mutations
156 Y 19 0 19 0.000 0.563 View mutations
157 T 19 0 19 0.001 0.854 View mutations
158 P 19 0 19 0.001 0.828 View mutations
159 S 19 0 19 0.002 0.840 View mutations
160 D 19 0 19 0.001 0.904 View mutations
161 G 19 0 19 0.011 0.780 View mutations
162 T 19 0 19 0.001 0.962 View mutations
163 Q 19 0 19 0.011 0.976 View mutations
164 K 19 0 19 0.033 0.972 View mutations
165 V 19 0 19 0.005 0.832 View mutations
166 T 19 0 19 0.023 1.000 View mutations
167 Y 19 0 19 0.003 0.809 View mutations
168 L 19 0 19 0.038 0.939 View mutations
169 V 19 0 19 0.004 0.600 View mutations
170 H 19 0 19 0.006 0.587 View mutations
171 N 17 2 19 0.135 0.695 View mutations
172 F 19 0 19 0.000 0.656 View mutations
173 E 19 0 19 0.030 0.764 View mutations
174 E 19 0 19 0.047 0.821 View mutations
175 G 19 0 19 0.002 0.694 View mutations