P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 N 0 19 19 1.000 0.800 View mutations
227 A 0 19 19 1.000 0.800 View mutations
228 C 0 19 19 1.000 0.712 View mutations
229 G 0 19 19 1.000 0.815 View mutations
230 L 0 19 19 1.000 0.733 View mutations
231 Y 0 19 19 1.000 0.752 View mutations
232 H 0 19 19 1.000 0.685 View mutations
233 K 0 19 19 1.000 0.711 View mutations
234 M 0 19 19 1.000 0.717 View mutations
235 N 0 19 19 1.000 0.823 View mutations
236 G 0 19 19 1.000 0.764 View mutations
237 Q 0 19 19 1.000 0.583 View mutations
238 N 0 19 19 1.000 0.642 View mutations
239 R 1 18 19 0.972 0.636 View mutations
240 P 0 19 19 0.999 0.724 View mutations
241 L 0 19 19 0.979 0.656 View mutations
242 I 0 19 19 0.996 0.622 View mutations
243 R 0 19 19 0.994 0.575 View mutations
244 P 0 19 19 0.943 0.663 View mutations
245 K 1 18 19 0.948 0.567 View mutations
246 K 1 18 19 0.944 0.563 View mutations
247 R 1 18 19 0.910 0.531 View mutations
248 L 1 18 19 0.921 0.483 View mutations
249 I 0 19 19 1.000 0.606 View mutations
250 V 0 19 19 0.980 0.692 View mutations